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KMID : 0377619770330030275
Korean Jungang Medical Journal
1977 Volume.33 No. 3 p.275 ~ p.280
Drug Resistance and R Plasmids in Salmonella Isolated from Dogs
ì°ïáûà/Lee, Jeong-Ho
ùÁÓÞêó/Ha, Tai-You
Abstract
Total of 19 strains of Salmonella isolated from mesenteric lymph nodes of dogs in 1975 were examined for drug resistance and distribution of R plasmids.
Of 19 isolates, 7 strains were classified as S. takasony, 6 strains as S. enteritidis, each 2 strains as S. paratyphi B and S. anatum, each 1 strains as S. typhimurium and S. bredeney.
Resistance was restricted to tetracycline (TC), streptomycin (SM) and ampicillin (AP), singly or in combination. Seven strains were resistant to TC, 6 strains to SM, and 2 strains to AP, indicating that 9 strains (47.4%) of the isolates were resistant to one or two drugs. No strain was resistant to chloramphenicol (CM), kanamycin (KM), gentamicin (GM) and nalidixic acid (N The resistant patterns were TC, AP, and TC SM.
Transfer experiment of drug resistance showed that of 9 resistant strains, 7 strains transferred part or all resistance to TC or TC SM, indicating 7 strains carried R plasmids determining TC, and TC SM.
The transfer frequency of TC resistance from Salmonella to E. coli varied between 0. 07 and 40% at 18 hours of incubation at 37¡ÆC and that of SM resistance varied between 4-6x10-3x0.04%.
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